The catecholamine neuron: Historical and future perspectives

Prog Neurobiol. 2010 Feb 9;90(2):75-81. doi: 10.1016/j.pneurobio.2009.10.014. Epub 2009 Oct 21.


My goals for this perspective are to enumerate what I consider to have been the major discoveries in the investigations of the central catecholamine neuron systems from the synaptic, cellular and systems physiological and neurohistochemical perspectives. To do so, I will emphasize here the synaptic and physiological aspects of the central noradrenergic (NE) system, considering both the past research and what we may expect to witness in the decades ahead.

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Catecholamines / physiology*
  • Central Nervous System / cytology*
  • Central Nervous System / physiology
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Neurobiology* / history
  • Neurobiology* / trends
  • Neurons / physiology*
  • Synaptic Transmission / physiology


  • Catecholamines