Complete genome sequence of Anaplasma marginale subsp. centrale

J Bacteriol. 2010 Jan;192(1):379-80. doi: 10.1128/JB.01330-09.


Anaplasma marginale subsp. centrale is a naturally attenuated subtype that has been used as a vaccine for a century. We sequenced the genome of this organism and compared it to those of virulent senso stricto A. marginale strains. The comparison markedly narrows the number of outer membrane protein candidates for development of a safer inactivated vaccine and provides insight into the diversity among strains of senso lato A. marginale.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anaplasma marginale / genetics*
  • Genome, Bacterial / genetics*
  • Molecular Sequence Data

Associated data

  • GENBANK/CP001759