PlnTFDB: updated content and new features of the plant transcription factor database

Nucleic Acids Res. 2010 Jan;38(Database issue):D822-7. doi: 10.1093/nar/gkp805. Epub 2009 Oct 25.


The Plant Transcription Factor Database (PlnTFDB; is an integrative database that provides putatively complete sets of transcription factors (TFs) and other transcriptional regulators (TRs) in plant species (sensu lato) whose genomes have been completely sequenced and annotated. The complete sets of 84 families of TFs and TRs from 19 species ranging from unicellular red and green algae to angiosperms are included in PlnTFDB, representing >1.6 billion years of evolution of gene regulatory networks. For each gene family, a basic description is provided that is complemented by literature references, and multiple sequence alignments of protein domains. TF or TR gene entries include information of expressed sequence tags, 3D protein structures of homologous proteins, domain architecture and cross-links to other computational resources online. Moreover, the different species in PlnTFDB are linked to each other by means of orthologous genes facilitating cross-species comparisons.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods*
  • Computational Biology / trends
  • Databases, Genetic*
  • Databases, Protein
  • Gene Expression Regulation, Plant
  • Gene Regulatory Networks
  • Genes, Plant*
  • Genome, Plant
  • Information Storage and Retrieval / methods
  • Internet
  • Plant Diseases / genetics
  • Plant Proteins / metabolism
  • Plants / metabolism*
  • Protein Structure, Tertiary
  • Software
  • Transcription Factors / metabolism*


  • Plant Proteins
  • Transcription Factors