Nutrition and cancer of the oral cavity and pharynx in north-east Italy

Int J Cancer. 1991 Jan 2;47(1):20-5. doi: 10.1002/ijc.2910470105.


The relation between dietary indicators and the risk of cancer of the oral cavity and pharynx was investigated in a case-control study conducted in Pordenone province, north-east Italy, on 302 cases (266 males and 36 females) and 699 controls admitted to hospital for acute, non-neoplastic and non-digestive disorders. Positive associations were observed, after allowing for occupation, smoking and drinking habits, with more frequent consumption of pasta or rice, polenta, cheese, eggs and pulses (odds ratios - ORs = 1.6, 2.1, 1.9, 1.9 and 2.0 for highest vs. lowest tertile), whereas reduced ORs emerged in subjects reporting more frequent consumption of carrots, fresh tomatoes and green peppers (ORs = 0.6, 0.5 and 0.5, respectively). Higher frequency of daily meals was also associated with a significantly elevated OR (1.7 for greater than or equal to 4 vs. less than or equal to 2 meals). The role of various indicator foods must be assessed in the context of the very high levels of alcohol consumption in the study area (greater than or equal to 8 alcoholic drinks/day in 2/3 cancer cases).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Alcohol Drinking
  • Case-Control Studies
  • Diet*
  • Environment
  • Female
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Mouth Neoplasms / epidemiology*
  • Pharyngeal Neoplasms / epidemiology*
  • Regression Analysis
  • Risk Factors
  • Smoking