Ocular blood flow assessment using continuous laser Doppler flowmetry

Acta Ophthalmol. 2010 Sep;88(6):622-9. doi: 10.1111/j.1755-3768.2009.01621.x.


This article describes the technique of continuous laser Doppler flowmetry (LDF) as applied to the measurement of the flux of red blood cells in the optic nerve head, iris and subfoveal choroid. Starting with the exposition of the physical principles underlying LDF, we first describe the various devices developed to perform LDF in these vascular beds. We then discuss the clinical protocols, blood flow parameters, calibration procedures, reproducibility and limitations of the LDF technique. Various problems still need to be solved in order to bring to light the full potential of LDF in the assessment of microcirculatory haemodynamics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Flow Velocity / physiology
  • Choroid / blood supply*
  • Eye Diseases / physiopathology*
  • Humans
  • Iris / blood supply*
  • Laser-Doppler Flowmetry / methods*
  • Optic Disk / blood supply*
  • Regional Blood Flow / physiology*