Molecular epidemiology of clade 1 influenza A viruses (H5N1), southern Indochina peninsula, 2004-2007

Emerg Infect Dis. 2009 Oct;15(10):1641-4. doi: 10.3201/eid1510.090115.


To determine the origin of influenza A virus (H5N1) epizootics in Cambodia, we used maximum-likelihood and Bayesian methods to analyze the genetic sequences of subtype H5N1 strains from Cambodia and neighboring areas. Poultry movements, rather than repeated reintroduction of subtype H5N1 viruses by wild birds, appear to explain virus circulation and perpetuation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Animals, Wild
  • Birds
  • Cambodia / epidemiology
  • Disease Outbreaks
  • Humans
  • Influenza A Virus, H5N1 Subtype / genetics
  • Influenza A Virus, H5N1 Subtype / isolation & purification*
  • Influenza in Birds / epidemiology
  • Influenza in Birds / virology*
  • Influenza, Human / epidemiology*
  • Influenza, Human / virology*
  • Molecular Epidemiology
  • Time Factors