Volume and distances of the maxillary sinus in craniofacial deformities with midfacial hypoplasia

Otolaryngol Head Neck Surg. 2009 Nov;141(5):614-20. doi: 10.1016/j.otohns.2009.08.018.


Objective: Craniofacial deformities (CFDs) frequently accompany midfacial hypoplasia. The authors evaluated characteristics of maxillary sinuses that had CFDs with variable degrees of midfacial hypoplasia.

Study design: Cross-sectional survey with chart review.

Setting: Department of Plastic and Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Subjects and methods: We investigated 40 patients with CFDs having midfacial hypoplasia. Study group 1 (SG 1) consisted of eight patients with Crouzon syndrome (16 maxillary sinuses). Study group 2 (SG 2) consisted of 10 patients with midfacial hypoplasia after palatoplasty (20 maxillary sinuses). Study group 3 (SG 3) consisted of 22 patients with Pruzansky grade I hemifacial microsomia (22 maxillary sinuses on the affected sides). Data on volume and three-dimensional distances (height, width, and depth) from computed tomography were collected and compared with each corresponding control group. Correlation coefficient between volume and the three distances was also calculated.

Results: The volume, height, width, and depth of the maxillary sinus were significantly decreased in SG 1 (P < 0.01). In SG 2, only the depth was significantly decreased (P < 0.05). In SG 3, there were no significant differences in any parameters. A multiple-regression analysis between the volume and the three distances showed a statistically significant relationship for width in SG 1, width and height in SG 2, and all distances in SG 3.

Conclusion: There were differences in the structure of the maxillary sinuses among patients with different CFDs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Craniofacial Abnormalities / pathology*
  • Craniofacial Dysostosis / pathology
  • Cross-Sectional Studies
  • Face / abnormalities*
  • Female
  • Humans
  • Male
  • Maxillary Sinus / pathology*
  • Middle Aged
  • Organ Size