Hemispheric synchronized sounds and perioperative analgesic requirements

Anesth Analg. 2010 Jan 1;110(1):208-10. doi: 10.1213/ANE.0b013e3181bea424. Epub 2009 Oct 27.

Abstract

Background: Data on the effect of Hemisync sounds on perioperative analgesic requirements are scant.

Methods: We randomized surgical outpatients into a treatment group that received Hemisync sounds (n = 20), a music group that received music (n = 20), and a control group that had a blank cassette tape (n = 20). All subjects underwent a controlled standardized propofol-nitrous-vecuronium and fentanyl general anesthesia.

Results: The treatment group had significantly reduced intraoperative fentanyl consumption (P < 0.05). Postoperatively, pain visual analog scale scores were significantly lower in the Hemisync group at 1 h (P = 0.02) and 24 h (P = 0.005). Subjects in the Hemisync group were also discharged earlier (P = 0.048).

Conclusion: The use of Hemisync sounds before and during general anesthesia reduces intraoperative analgesic requirements, postoperative pain scores, and discharge time.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Acoustic Stimulation*
  • Adolescent
  • Adult
  • Aged
  • Ambulatory Surgical Procedures
  • Analgesics / administration & dosage*
  • Analgesics / therapeutic use*
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / therapeutic use
  • Anesthesia, General
  • Cortical Synchronization
  • Double-Blind Method
  • Endpoint Determination
  • Female
  • Fentanyl / administration & dosage
  • Fentanyl / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Pain / drug therapy*
  • Pain / prevention & control
  • Pain Measurement
  • Pain, Postoperative / drug therapy
  • Pain, Postoperative / prevention & control
  • Perioperative Care*
  • Young Adult

Substances

  • Analgesics
  • Analgesics, Opioid
  • Fentanyl