Alcohol intake and risk of thyroid cancer in the NIH-AARP Diet and Health Study

Br J Cancer. 2009 Nov 3;101(9):1630-4. doi: 10.1038/sj.bjc.6605337. Epub 2009 Sep 29.


Background: Certain studies suggest that alcohol may reduce the risk of thyroid cancer in women, but the effect in men remains unclear.

Methods: We analysed the association between alcohol and thyroid cancer in a large (n=490 159) prospective NIH-AARP Diet and Health Study with self-reported beer, wine, and liquor intakes.

Results: Over 7.5 years of follow-up (median), 170 men and 200 women developed thyroid cancer. Overall, the thyroid cancer risk decreased with greater alcohol consumption (> or =2 drinks per day vs none, relative risk=0.57, 95% CI 0.36-0.89, P-trend=0.01).

Conclusions: These results suggest a potential protective role for alcohol consumption in thyroid cancer.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Aged
  • Alcohol Drinking*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk
  • Thyroid Neoplasms / prevention & control*