Splenic angiomatoid nodular transformation in a child with increased erythrocyte sedimentation rate

Pediatr Hematol Oncol. Oct-Nov 2009;26(7):533-7. doi: 10.1080/07357900903114010.


An 11-year-old girl was referred to the authors' hospital with a complaint of growth retardation. Physical examination revealed splenomegaly. Laboratory examination revealed increased sedimentation rate. Her imaging studies showed a splenic mass. Splenectomy was performed and histopathological examination revealed sclerosing angiomatoid nodular transformation (SANT) of the spleen. The disease rarely affects children but it could cause growth retardation and increased sedimentation rate, mimicking the chronic inflammatory diseases.

Publication types

  • Case Reports

MeSH terms

  • Blood Sedimentation
  • Child
  • Diagnosis, Differential
  • Female
  • Histiocytoma, Benign Fibrous / blood*
  • Histiocytoma, Benign Fibrous / pathology*
  • Histiocytoma, Benign Fibrous / surgery
  • Humans
  • Inflammation / blood
  • Inflammation / pathology
  • Inflammation / surgery
  • Splenectomy
  • Splenic Neoplasms / blood*
  • Splenic Neoplasms / pathology*
  • Splenic Neoplasms / surgery