Toward the Early Diagnosis of Systemic Sclerosis: Warning Signs the Practitioner Needs to Recognize

Minn Med. 2009 Sep;92(9):42-4.


Systemic sclerosis, or scleroderma, is a rare condition that first presents with symptoms common to many other diseases. Because of this, diagnosing it can be difficult and take time.This article describes warning signs of possible incipient scleroderma as well as tests that can help the primary care provider identify this serious autoimmune disorder.

MeSH terms

  • Antibodies, Antinuclear / blood
  • Diagnosis, Differential
  • Early Diagnosis
  • Humans
  • Physical Examination
  • Primary Health Care
  • Scleroderma, Systemic / diagnosis*


  • Antibodies, Antinuclear