Exploring chemical space with aptamers

J Med Chem. 2009 Nov 26;52(22):6951-7. doi: 10.1021/jm9014789.
No abstract available

Publication types

  • Address
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Aptamers, Nucleotide / chemistry*
  • Aptamers, Nucleotide / metabolism*
  • Aptamers, Nucleotide / pharmacology
  • Aptamers, Nucleotide / therapeutic use
  • Awards and Prizes*
  • Drug Design
  • Guanine Nucleotide Exchange Factors / chemistry
  • Guanine Nucleotide Exchange Factors / metabolism
  • HIV Reverse Transcriptase / antagonists & inhibitors
  • HIV-1 / enzymology
  • Humans
  • Mice
  • Molecular Sequence Data
  • RNA, Catalytic / metabolism
  • Reverse Transcriptase Inhibitors / chemistry
  • Reverse Transcriptase Inhibitors / pharmacology

Substances

  • Aptamers, Nucleotide
  • Guanine Nucleotide Exchange Factors
  • RNA, Catalytic
  • Reverse Transcriptase Inhibitors
  • hammerhead ribozyme
  • HIV Reverse Transcriptase