Sleep disorders in patients with multiple sclerosis

Steven D Brass; Pierre Duquette; Joëlle Proulx-Therrien; Sanford Auerbach

doi:10.1016/j.smrv.2009.07.005

Sleep disorders in patients with multiple sclerosis

Sleep Med Rev. 2010 Apr;14(2):121-9. doi: 10.1016/j.smrv.2009.07.005. Epub 2009 Oct 29.

Authors

Steven D Brass¹, Pierre Duquette, Joëlle Proulx-Therrien, Sanford Auerbach

Affiliation

¹ Co-Director of Sleep Medicine, Department of Neurology, UC Davis School of Medicine, 4860 Y Street, Suite 0100, Sacramento, CA 95817, USA. steven.brass@ucdmc.ucdavis.edu

PMID: 19879170
DOI: 10.1016/j.smrv.2009.07.005

Abstract

Patients with multiple sclerosis (MS) often have unrecognized sleep disorders at higher frequency than the general population. Sleep disorders such as sleep disordered breathing, insomnia, REM sleep behavior disorder, narcolepsy and restless legs syndrome have all been reported in the MS population. Notably, the most common symptom of MS is "fatigue," which itself has been correlated with sleep disturbances. Sleep disorders may impact the quality of life of the MS patient population. This paper reviews the association of sleep disorders with MS, and discusses the association of sleep disruption with MS fatigue.

Publication types

Review

MeSH terms

Fatigue / etiology
Fatigue / physiopathology
Humans
Multiple Sclerosis / complications*
Multiple Sclerosis / physiopathology
REM Sleep Behavior Disorder / etiology
REM Sleep Behavior Disorder / physiopathology
Restless Legs Syndrome / etiology
Restless Legs Syndrome / physiopathology
Sleep Apnea Syndromes / etiology
Sleep Apnea Syndromes / physiopathology
Sleep Initiation and Maintenance Disorders / etiology
Sleep Initiation and Maintenance Disorders / physiopathology
Sleep Wake Disorders / etiology*
Sleep Wake Disorders / physiopathology