Comparison between CT- and FDG-PET-defined target volumes for radiotherapy planning in head-and-neck cancers

Radiother Oncol. 2009 Dec;93(3):479-82. doi: 10.1016/j.radonc.2009.09.010. Epub 2009 Oct 31.


Nine patients with head-and-neck cancer underwent computerized tomography (CT) simulation and [(18)F]-fluorodeoxyglucose positron emission tomography (FDG-PET) to compare the radiotherapy target volumes. The PET volumes were delineated with an automatic segmentation based on the source-to-background ratio. The volume comparison showed a reduction and qualitative discrepancies between the PET- and CT-volumes.

Publication types

  • Comparative Study

MeSH terms

  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / radiotherapy*
  • Fluorodeoxyglucose F18*
  • Head and Neck Neoplasms / diagnostic imaging
  • Head and Neck Neoplasms / radiotherapy*
  • Humans
  • Phantoms, Imaging
  • Positron-Emission Tomography*
  • Radiopharmaceuticals*
  • Radiotherapy Planning, Computer-Assisted*
  • Tomography, X-Ray Computed*


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18