In vivo biofilm composition of Aspergillus fumigatus

Cell Microbiol. 2010 Mar;12(3):405-10. doi: 10.1111/j.1462-5822.2009.01409.x. Epub 2009 Nov 4.

Abstract

The in vivo composition of the mycelial extracellular matrix (ECM) of Aspergillus fumigatus during host invasion is reported here for the first time. A new galactosaminogalactan and the galactomannan were the major polysaccharides of the in vivo ECM. The composition of the ECM in vivo varied with the aspergillosis pathologies.

MeSH terms

  • Animals
  • Aspergillus fumigatus / growth & development
  • Aspergillus fumigatus / metabolism
  • Aspergillus fumigatus / physiology*
  • Biofilms / growth & development*
  • Extracellular Matrix / chemistry*
  • Humans
  • Mannans / analysis
  • Mice
  • Polysaccharides / analysis

Substances

  • Mannans
  • Polysaccharides
  • galactosaminogalactan
  • galactomannan