Mediating the effect of self-care management intervention in type 2 diabetes: a meta-analysis of 47 randomised controlled trials

Patient Educ Couns. 2010 Jul;80(1):29-41. doi: 10.1016/j.pec.2009.09.033. Epub 2009 Nov 10.

Abstract

Objective: To perform a meta-analysis assessing the effects of self-care management interventions in improving glycaemic control in type 2 diabetes by analysing the impact of different study characteristics on the effect size.

Methods: A literature search in eight scientific databases up to November 2007 included original studies of randomised controlled trials involving adult patients diagnosed with type 2 diabetes and evaluating a self-care management intervention.

Results: The 47 included studies yielded 7677 participants. The analysis showed a 0.36% (95% CI 0.21-0.51) improvement in glycaemic control in people who received self-care management treatment. In the univariate meta-regression sample size (effect size 0.42%, p=0.007) and follow-up period (effect size 0.49%, p=0.017) were identified to have significant effect on the effect size in favour of small studies and short follow-up. For type of intervention and duration of intervention there was a non-significant effect on effect size in favour of educational techniques and short interventions.

Conclusion: In type 2 diabetes, there are improvements in glycaemic control in people who receive self-care management treatment with a small advantage to intervention with an educational approach.

Practice implications: Further research on frequency and duration of intervention may provide useful information to identify the most effective regime.

Publication types

  • Meta-Analysis
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Blood Glucose / metabolism
  • Blood Glucose Self-Monitoring
  • Diabetes Mellitus, Type 2 / therapy*
  • Glycated Hemoglobin A / metabolism
  • Humans
  • Life Style
  • Patient Education as Topic*
  • Randomized Controlled Trials as Topic*
  • Self Care*
  • Treatment Outcome

Substances

  • Blood Glucose
  • Glycated Hemoglobin A