Oral fluid tests for screening of human immunodeficiency virus-exposed infants

Pediatr Infect Dis J. 2010 Feb;29(2):169-72. doi: 10.1097/INF.0b013e3181b9a19c.


In high human immunodeficiency virus (HIV) prevalence settings, routine screening of infants attending immunization visits could improve identification of HIV-exposed infants to receive an early diagnosis and appropriate interventions. This first assessment of 2 rapid oral fluid HIV tests in early infancy demonstrates a sensitivity of <90% for detection of HIV-exposure resulting in failure to detect at least 1 in 10 HIV-infected infants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • HIV / immunology*
  • HIV Antibodies / analysis*
  • HIV Infections / diagnosis*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mass Screening / methods*
  • Reagent Kits, Diagnostic
  • Saliva / immunology*
  • Sensitivity and Specificity


  • HIV Antibodies
  • Reagent Kits, Diagnostic