Abstract
Locked-in syndrome is characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral horizontal gaze palsy and anarthria, with preserved consciousness. It is due to a ventral pontine lesion following a basilar artery occlusion. We report the first Indian case report of locked-in syndrome, a 10-year old girl in whom the syndome was preceded by a 'herald hemiparesis'. Although the exact etiology for the basilar artery occlusion could not be determined, treatment with low molecular weight heparin and warfarin was followed by partial recovery.
MeSH terms
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Arterial Occlusive Diseases / complications
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Arterial Occlusive Diseases / diagnosis*
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Arterial Occlusive Diseases / drug therapy
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Basilar Artery / pathology*
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Child
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Female
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Follow-Up Studies
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Heparin, Low-Molecular-Weight / therapeutic use
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Humans
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India
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Magnetic Resonance Angiography
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Neuropsychological Tests
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Quadriplegia / diagnosis
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Quadriplegia / drug therapy
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Quadriplegia / etiology*
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Rare Diseases
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Recovery of Function
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Severity of Illness Index
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Stroke / complications
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Stroke / diagnosis*
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Stroke / drug therapy
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Treatment Outcome
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Warfarin / therapeutic use
Substances
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Heparin, Low-Molecular-Weight
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Warfarin