Abstract
Two brothers simultaneously exposed to moldy hay, who developed differing forms of Aspergillus-related lung disease, are presented. Patient 1 developed a true case of hypersensitivity lung disease, whereas his brother developed invasive aspergillosis with bronchoalveolar lavage eosinophilia and unusual pathologic features including tissue eosinophilia. The possible overlap between hypersensitivity pneumonitis and invasive aspergillosis in the immunocompetent host is discussed.
MeSH terms
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Adult
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Alveolitis, Extrinsic Allergic / diagnostic imaging
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Alveolitis, Extrinsic Allergic / etiology*
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Antifungal Agents / therapeutic use
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Aspergillosis / complications*
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Aspergillosis / diagnostic imaging
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Aspergillosis / drug therapy
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Biopsy
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Bronchoalveolar Lavage Fluid / microbiology
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Bronchoalveolar Lavage Fluid / pathology
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Eosinophilia / complications
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Granuloma / complications
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Granuloma / pathology
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Humans
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Lung / pathology
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Lung Diseases / complications*
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Lung Diseases / diagnostic imaging
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Male
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Radiography, Thoracic