Quality of life after septic illness

J Crit Care. 2010 Sep;25(3):406-12. doi: 10.1016/j.jcrc.2009.10.001. Epub 2009 Nov 14.


Purpose: The study was undertaken to evaluate the quality of life of survivors of septic illness.

Materials and methods: A questionnaire survey of survivors of septic illness (experimental group) and acute myocardial infarction (control group) was conducted using information from the Adult Neuropsychological History and the Sickness Impact Profile forms. Eight patients diagnosed with sepsis (using the Bone et al 1992 criteria [Bone RC, Sprung CL, Sibbald WJ. Crit Care Med 1992;20:724-726]) and 15 patients diagnosed with acute myocardial infarction participated in the study.

Results: On the Sickness Impact Profile, greater difficulty with work was reported in the sepsis group than in the cardiac control group (P < .04). When retired individuals were excluded from the analysis, individuals in the sepsis group reported more symptoms on the sensory, physical, and behavior sections of the Adult Neuropsychological History form and greater difficulty with sleep and rest, emotional behavior, body care and movement, and physical and psychosocial functioning on the Sickness Impact Profile. As well, more individuals in the sepsis than the control group endorsed symptoms related to problem solving, concentration, memory, sensory, and physical ability.

Conclusions: Individuals surviving sepsis may have problems with physical, sensory, emotional, and cognitive functioning that become most apparent when involved in more challenging activities, such as working.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Quality of Life*
  • Sepsis*
  • Sickness Impact Profile
  • Surveys and Questionnaires
  • Survivors*
  • Work