The hedgehog pathway and pancreatic cancer

N Engl J Med. 2009 Nov 19;361(21):2094-6. doi: 10.1056/NEJMcibr0905857.
No abstract available

MeSH terms

  • Animals
  • Disease Models, Animal
  • Hedgehog Proteins / antagonists & inhibitors*
  • Hedgehog Proteins / metabolism
  • Humans
  • Mice
  • Pancreatic Neoplasms / drug therapy*
  • Pancreatic Neoplasms / metabolism
  • Receptors, G-Protein-Coupled / antagonists & inhibitors*
  • Signal Transduction / drug effects
  • Smoothened Receptor
  • Veratrum Alkaloids / therapeutic use*

Substances

  • Hedgehog Proteins
  • IPI-926
  • Receptors, G-Protein-Coupled
  • Smo protein, mouse
  • Smoothened Receptor
  • Veratrum Alkaloids