Vaccines Against Tularemia

Hum Vaccin. 2009 Dec;5(12):832-8. doi: 10.4161/hv.10297. Epub 2009 Dec 11.

Abstract

Francisella tularensis is a Category A select agent for which vaccine and countermeasure development are a priority. In the past eight years, renewed interest in this pathogen has led to the generation of an enormous amount of new data on both the pathogen itself and its interaction with host cells. This information has fostered the development of various vaccine candidates including acellular subunit, killed whole cell and live attenuated. This review summarizes the progress and promise of these various candidates.

Publication types

  • Review

MeSH terms

  • Bacterial Vaccines / immunology*
  • Bioterrorism
  • Francisella tularensis / immunology*
  • Humans
  • Tularemia / prevention & control*
  • Vaccines, Acellular / immunology
  • Vaccines, Attenuated / immunology
  • Vaccines, Inactivated / immunology

Substances

  • Bacterial Vaccines
  • Vaccines, Acellular
  • Vaccines, Attenuated
  • Vaccines, Inactivated