NIR-VCD, vibrational circular dichroism in the near-infrared: experiments, theory and calculations

Chirality. 2009:21 Suppl 1:E242-52. doi: 10.1002/chir.20805.

Abstract

The first well documented experiments of Near Infrared Vibrational Circular Dichroism (NIR-VCD) were performed around 1975. We review the thirty year history of NIR-VCD, encompassing both instrumental development and theoretical/computational methods that allow interpretation of experimental spectra, harvesting useful structural information therefrom. We hope to stimulate interest in this still scarcely explored spectroscopy of chiral molecules.

Publication types

  • Review

MeSH terms

  • Camphanes / chemistry
  • Circular Dichroism / instrumentation*
  • Circular Dichroism / methods*
  • Equipment Design
  • Models, Chemical
  • Models, Molecular
  • Molecular Conformation
  • Molecular Structure
  • Norbornanes / chemistry
  • Solutions
  • Spectrophotometry, Infrared / methods
  • Stereoisomerism
  • Vibration

Substances

  • Camphanes
  • Norbornanes
  • Solutions
  • fenchol
  • isoborneol