Experimental study of the excitation functions of proton induced nuclear reactions on (167)Er for production of medically relevant (167)Tm

F Tárkányi; A Hermanne; S Takács; B Király; I Spahn; A V Ignatyuk

doi:10.1016/j.apradiso.2009.10.043

Experimental study of the excitation functions of proton induced nuclear reactions on (167)Er for production of medically relevant (167)Tm

Appl Radiat Isot. 2010 Feb;68(2):250-5. doi: 10.1016/j.apradiso.2009.10.043. Epub 2009 Oct 28.

Authors

F Tárkányi¹, A Hermanne, S Takács, B Király, I Spahn, A V Ignatyuk

Affiliation

¹ Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), 4026 Debrecen, Bem ter 18/c, Hungary.

PMID: 19932028
DOI: 10.1016/j.apradiso.2009.10.043

Abstract

(167)Tm (T(1/2)=9.25d) is a candidate radioisotope for medical therapy and diagnostics due to its Auger-electron and low-energy X- and gamma-ray emission. Excitation functions of the (167)Er(p,n)(167)Tm reaction and (168)Er(p,n)(168)Tm, (167)Er(p,2n)(166)Tm, (166)Er(p,2n)(165)Tm disturbing reactions were measured up to 15MeV by using the stacked foil irradiation technique and gamma-ray spectroscopy. The measured excitation functions agree well with the results of ALICE-IPPE, EMPIRE-II and TALYS nuclear reaction model codes. The thick target yield of (167)Tm in the 15-8MeV energy range is 6.9MBq/microAh. A short comparison of charged particle production routes of (167)Tm is given.

MeSH terms

Computer Simulation
Erbium / chemistry*
Erbium / radiation effects
Isotopes / chemistry*
Isotopes / radiation effects
Models, Chemical*
Photons
Radioisotopes
Radiopharmaceuticals / chemical synthesis*
Radiopharmaceuticals / radiation effects
Thulium / chemistry*
Thulium / radiation effects

Substances

Isotopes
Radioisotopes
Radiopharmaceuticals
Erbium
Thulium