Neurologic presentations of sarcoidosis

Neurol Clin. 2010 Feb;28(1):185-98. doi: 10.1016/j.ncl.2009.09.012.


Neurosarcoidosis is a diagnostic consideration in diverse clinical settings. Efforts should be made to secure pathologic confirmation of systemic sarcoidosis; only rarely is central nervous system (CNS) pathologic confirmation available. CNS infection and malignancy should be reasonably excluded before making a diagnosis of CNS sarcoidosis. Corticosteroid therapy alone may not be sufficient to treat neurosarcoidosis; adjunct immunosuppressive agents are increasingly used to achieve an optimal clinical outcome.

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Nervous System Diseases / complications*
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / therapy
  • Sarcoidosis / complications*
  • Sarcoidosis / diagnosis
  • Sarcoidosis / therapy