Prevention of severe cutaneous adverse drug reactions: the emerging value of pharmacogenetic screening

CMAJ. 2010 Mar 23;182(5):476-80. doi: 10.1503/cmaj.090401. Epub 2009 Nov 23.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alleles
  • Allopurinol / adverse effects*
  • Anticonvulsants / adverse effects
  • Asian Continental Ancestry Group / genetics
  • Carbamazepine / adverse effects
  • China
  • Cyclosporine / therapeutic use
  • Drug Hypersensitivity / genetics*
  • Genetic Predisposition to Disease
  • Genetic Testing*
  • Gout Suppressants / adverse effects*
  • HLA-B Antigens / genetics
  • Humans
  • Immunization, Passive
  • Immunosuppressive Agents / therapeutic use
  • Keratoconjunctivitis / chemically induced
  • Keratoconjunctivitis / drug therapy
  • Male
  • Stevens-Johnson Syndrome / chemically induced*
  • Stevens-Johnson Syndrome / drug therapy
  • Stevens-Johnson Syndrome / etiology*
  • Urethritis / chemically induced
  • Urethritis / drug therapy

Substances

  • Anticonvulsants
  • Gout Suppressants
  • HLA-B Antigens
  • Immunosuppressive Agents
  • Carbamazepine
  • Allopurinol
  • Cyclosporine