Nephroptosis in a young woman with joint laxity

Nat Rev Nephrol. 2009 Dec;5(12):722-5. doi: 10.1038/nrneph.2009.169.


Background: A 25-year-old woman was evaluated repeatedly from 10 months following her first pregnancy and delivery for recurrent episodes of lower right quadrant abdominal pain, hematuria and a sensation of mass. Despite investigations by several physicians over a 7 month period no clear diagnosis had been made, but a psychosomatic disorder or possible periodic blocked bowel had been suggested, after which the patient requested a consultation with a nephrologist. Her history indicated joint laxity syndrome and a mitral valve prolapse. She was undergoing continuing evaluation for a possible rheumatic condition.

Investigations: Full history, physical examination, and intravenous pyelography.

Diagnosis: Nephroptosis of the right kidney.

Intervention: Exercises were prescribed to strengthen her abdominal musculature and she was advised to wear an elastic abdominal corset during the daytime. The patient is currently considering surgical intervention.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abdominal Pain / diagnostic imaging
  • Abdominal Pain / etiology
  • Adult
  • Female
  • Humans
  • Joint Instability / etiology*
  • Kidney Diseases / complications*
  • Kidney Diseases / diagnostic imaging*
  • Urography*