Amusia as an early manifestation of frontotemporal dementia caused by a novel progranulin mutation

J Neurol. 2010 Mar;257(3):475-7. doi: 10.1007/s00415-009-5393-y.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age of Onset
  • Aged
  • Cognition Disorders / genetics
  • Cognition Disorders / pathology
  • Cognition Disorders / physiopathology
  • DNA Mutational Analysis
  • Disease Progression
  • Fatal Outcome
  • Female
  • Frontotemporal Dementia / genetics*
  • Frontotemporal Dementia / pathology*
  • Frontotemporal Dementia / physiopathology
  • Genetic Predisposition to Disease
  • Humans
  • Inclusion Bodies / metabolism
  • Inclusion Bodies / pathology
  • Intercellular Signaling Peptides and Proteins / genetics*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Music / psychology*
  • Mutation
  • Neurons / metabolism
  • Neurons / pathology
  • Perceptual Disorders / genetics*
  • Perceptual Disorders / pathology*
  • Perceptual Disorders / physiopathology
  • Pitch Discrimination / physiology
  • Progranulins
  • Siblings
  • tau Proteins / genetics

Substances

  • GRN protein, human
  • Intercellular Signaling Peptides and Proteins
  • Progranulins
  • tau Proteins