Eradication of Enterococcus faecalis by phage therapy in chronic bacterial prostatitis--case report

Folia Microbiol (Praha). 2009 Sep;54(5):457-61. doi: 10.1007/s12223-009-0064-z. Epub 2009 Nov 24.


The treatment of three patients suffering from chronic bacterial prostatitis who were qualified for an experimental phage therapy protocol managed at the Phage Therapy Unit in Wrocław is described. They had previously been treated unsuccessfully with long-term targeted antibiotics, autovaccines, and laser biostimulation. Rectal application of phage lysates targeted against Enterococcus faecalis cultured from the prostatic fluid gave encouraging results regarding bacterial eradication, abatement of clinical symptoms of prostatitis, and lack of early disease recurrence.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bacteriophages / chemistry*
  • Bacteriophages / physiology
  • Biological Therapy*
  • Enterococcus faecalis / isolation & purification
  • Enterococcus faecalis / virology*
  • Gram-Positive Bacterial Infections / microbiology
  • Gram-Positive Bacterial Infections / therapy*
  • Humans
  • Male
  • Prostatitis / microbiology
  • Prostatitis / therapy*