Aloe vera as a biologically active vehicle for hydrocortisone acetate

J Am Podiatr Med Assoc. 1991 Jan;81(1):1-9. doi: 10.7547/87507315-81-1-1.

Abstract

Aloe vera, as a biological vehicle for hydrocortisone 21-acetate, was tested topically and systemically against acute inflammation. Systemically, the combination of A. vera and hydrocortisone produced a maximum 88.1% inhibition of edema. Polymorphonuclear leukocyte infiltration was reduced 91.1%. The topical inhibition of edema peaked at 97%. The possibility that A. vera has significant potential as a biologically active vehicle for steroids is discussed.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Administration, Topical
  • Aloe*
  • Animals
  • Anti-Inflammatory Agents / administration & dosage*
  • Anti-Inflammatory Agents / pharmacology
  • Female
  • Hydrocortisone / administration & dosage
  • Hydrocortisone / analogs & derivatives*
  • Hydrocortisone / pharmacology
  • Inflammation / drug therapy*
  • Male
  • Mice
  • Pharmaceutical Vehicles
  • Plants, Medicinal*
  • Rats
  • Rats, Inbred Strains

Substances

  • Anti-Inflammatory Agents
  • Pharmaceutical Vehicles
  • hydrocortisone acetate
  • Hydrocortisone