Renal potassium transport: the pioneering studies of Gerhard Giebisch

Am J Physiol Renal Physiol. 2010 Feb;298(2):F233-4. doi: 10.1152/ajprenal.00669.2009. Epub 2009 Nov 25.

Abstract

This essay looks at the historical significance of six APS Classic Papers that are freely available on line: Malnic G, Klose RM, Giebisch G. Micropuncture study of renal potassium excretion in the rat. Am J Physiol 206: 674–686, 1964 (http://ajplegacy.physiology.org/cgi/reprint/206/4/674). Malnic G, Klose RM, Giebisch G. Micropuncture study of distal tubular potassium and sodium transport in rat nephron. Am J Physiol 211: 529–547, 1966 (http://ajplegacy.physiology.org/cgi/reprint/211/3/529). Malnic G, Klose RM, Giebisch G. Microperfusion study of distal tubular potassium and sodium transfer in rat kidney. Am J Physiol 211: 548–559, 1966 (http://ajplegacy.physiology.org/cgi/reprint/211/3/548). Duarte CG, Chomety F, Giebisch G. Effect of amiloride, ouabain, and furosemide on distal tubular function in the rat. Am J Physiol 221: 632–640, 1971 (http://ajplegacy.physiology.org/cgi/reprint/221/2/632). Malnic G, De Mello Aires M, Giebisch G. Potassium transport across renal distal tubules during acid-base disturbances. Am J Physiol 221: 1192–1208, 1971 (http://ajplegacy.physiology.org/cgi/reprint/221/4/1192). Wright FS, Strieder N, Fowler NB, Giebisch G. Potassium secretion by distal tubule after potassium adaptation. Am J Physiol 221: 437–448, 1971 (http://ajplegacy.physiology.org/cgi/reprint/221/2/437).

Publication types

  • Biography
  • Editorial
  • Historical Article
  • Portrait
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Biological Transport
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Kidney / metabolism*
  • Nephrology / history*
  • Potassium / metabolism*

Substances

  • Potassium

Personal name as subject

  • Gerhard Giebisch