[Current strategies in radiotherapy for cervical and endometrial carcinoma]

Vopr Onkol. 2009;55(4):471-3.
[Article in Russian]

Abstract

We used combinations of taxan-based neoadjuvant and adjuvant full-dose chemotherapy and aggressive combined radiotherapy including clinical target volume extension, increased total dosage, hyperthermia, cryo- and local chemotherapy as radiosensitizers, for treatment of invasive and locally-advanced breast cancer or endometrial carcinoma with poor prognosis. 3D-ultrasound/CT/MRI--based designing of radiotherapy and monitoring of dynamic definition of target volume and "high risk volume" in organs at risk in cases of tumor progression was an indispensable measure. As a result, no local recurrence was reported in 73% for 36 months.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / administration & dosage
  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy*
  • Breast Neoplasms / therapy
  • Carcinoma / radiotherapy*
  • Carcinoma / secondary
  • Carcinoma / therapy
  • Chemotherapy, Adjuvant
  • Cryotherapy
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / radiotherapy*
  • Endometrial Neoplasms / therapy
  • Female
  • Humans
  • Hyperthermia, Induced
  • Imaging, Three-Dimensional
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neoadjuvant Therapy / methods*
  • Neoplasm Recurrence, Local / prevention & control*
  • Neoplasm Staging
  • Prognosis
  • Radiation-Sensitizing Agents / therapeutic use
  • Radiotherapy Dosage
  • Radiotherapy, Adjuvant
  • Risk Assessment
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / radiotherapy*
  • Uterine Cervical Neoplasms / therapy

Substances

  • Antineoplastic Agents
  • Radiation-Sensitizing Agents