Xylitol gum and maternal transmission of mutans streptococci

J Dent Res. 2010 Jan;89(1):56-60. doi: 10.1177/0022034509352958.

Abstract

An important caries prevention strategy for children includes measures to interfere with transmission of mutans streptococci (MS). This study confirmed the effectiveness of maternal early exposure to xylitol chewing gum on mother-child transmission of MS. After screening, 107 pregnant women with high salivary MS were randomized into two groups: xylitol gum (Xylitol; n = 56) and no gum (Control; n = 51) groups. Maternal chewing started at the sixth month of pregnancy and terminated 13 months later in the Xylitol group. Outcome measures were the presence of MS in saliva or plaque of the children until age 24 months. The Xylitol-group children were significantly less likely to show MS colonization than Control-group children aged 9-24 months. The Control-group children acquired MS 8.8 months earlier than those in the Xylitol group, suggesting that maternal xylitol gum chewing in Japan shows beneficial effects similar to those demonstrated in Nordic countries.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cariostatic Agents / administration & dosage
  • Chewing Gum
  • Chi-Square Distribution
  • Child, Preschool
  • Colony Count, Microbial
  • Dental Caries / microbiology
  • Dental Caries / prevention & control*
  • Dental Caries Susceptibility / drug effects
  • Dental Plaque / microbiology
  • Dental Plaque / prevention & control
  • Female
  • Humans
  • Infant
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Longitudinal Studies
  • Mothers*
  • Mouth / microbiology
  • Pregnancy
  • Preventive Dentistry
  • Single-Blind Method
  • Statistics, Nonparametric
  • Streptococcal Infections / microbiology
  • Streptococcal Infections / prevention & control
  • Streptococcal Infections / transmission*
  • Streptococcus mutans / drug effects
  • Streptococcus mutans / isolation & purification
  • Sweetening Agents / administration & dosage*
  • Xylitol / administration & dosage*

Substances

  • Cariostatic Agents
  • Chewing Gum
  • Sweetening Agents
  • Xylitol