Infrequent replication of parvovirus B19 and erythrovirus genotypes 2 and 3 among HIV-infected patients with chronic anemia

Clin Infect Dis. 2010 Jan 1;50(1):115-8. doi: 10.1086/649004.

Abstract

We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia. We screened the serum samples of 428 patients by specific ultrasensitive real-time polymerase chain reaction assay. Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anemia / blood
  • Anemia / complications
  • Anemia / virology*
  • Chronic Disease
  • Cohort Studies
  • DNA, Viral / blood
  • Erythrovirus / isolation & purification
  • Erythrovirus / physiology*
  • Female
  • HIV Infections / blood
  • HIV Infections / complications
  • HIV Infections / virology*
  • Humans
  • Male
  • Middle Aged
  • Parvoviridae Infections / blood
  • Parvoviridae Infections / complications
  • Parvoviridae Infections / virology
  • Parvovirus B19, Human / isolation & purification
  • Parvovirus B19, Human / physiology*
  • Polymerase Chain Reaction
  • Virus Replication*

Substances

  • DNA, Viral