Abstract
We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia. We screened the serum samples of 428 patients by specific ultrasensitive real-time polymerase chain reaction assay. Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anemia / blood
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Anemia / complications
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Anemia / virology*
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Chronic Disease
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Cohort Studies
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DNA, Viral / blood
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Erythrovirus / isolation & purification
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Erythrovirus / physiology*
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Female
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HIV Infections / blood
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HIV Infections / complications
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HIV Infections / virology*
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Humans
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Male
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Middle Aged
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Parvoviridae Infections / blood
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Parvoviridae Infections / complications
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Parvoviridae Infections / virology
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Parvovirus B19, Human / isolation & purification
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Parvovirus B19, Human / physiology*
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Polymerase Chain Reaction
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Virus Replication*