Within-household sharing of a fluoroquinolone-resistant Escherichia coli sequence type ST131 strain causing pediatric osteoarticular infection

Pediatr Infect Dis J. 2010 May;29(5):473-5. doi: 10.1097/INF.0b013e3181c89bd7.

Abstract

A fluoroquinolone-resistant Escherichia coli strain of sequence type ST131 caused severe septic arthritis and contiguous osteomyelitis in an 8-month-old girl, and colonized the girl's healthy mother, who shared a different fecal E. coli strain with the father. Within-household transmission can contribute to the dissemination of the emerging, multidrug-resistant ST131 clonal group, which has evident invasive potential for otherwise-healthy children.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Typing Techniques
  • Carrier State / microbiology
  • Cluster Analysis
  • DNA Fingerprinting
  • DNA, Bacterial / genetics
  • Drug Resistance, Bacterial*
  • Electrophoresis, Gel, Pulsed-Field
  • Escherichia coli / classification*
  • Escherichia coli / drug effects*
  • Escherichia coli / isolation & purification
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / transmission*
  • Family Characteristics
  • Family Health
  • Female
  • Fluoroquinolones / pharmacology*
  • Gastrointestinal Tract / microbiology
  • Genotype
  • Humans
  • Infant
  • Male
  • Osteoarthritis / microbiology*

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • Fluoroquinolones