For this issue of Journal, a few recent publications that discuss disorders of motor unit (motor neuron, nerve, neuromuscular junction, and muscle) are selected. Articles about amyotrophic lateral sclerosis, Guillain-Barré syndrome, hereditary neuropathies, myasthenia gravis, and myopathies that convey a salient clinical lesson are discussed. There have been many other excellent publications in the past few months, but the space constrains do not allow to include them all.