The Renewed Potential for Folate Antagonists in Contemporary Cancer Chemotherapy

J Med Chem. 1991 Feb;34(2):479-85. doi: 10.1021/jm00106a001.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Folic Acid / analogs & derivatives*
  • Folic Acid / therapeutic use
  • Folic Acid Antagonists* / therapeutic use*
  • Humans
  • Neoplasms / drug therapy*
  • Quinazolines / therapeutic use*
  • Structure-Activity Relationship
  • Thymidylate Synthase / antagonists & inhibitors*

Substances

  • Antineoplastic Agents
  • Folic Acid Antagonists
  • Quinazolines
  • CB 3717
  • Folic Acid
  • Thymidylate Synthase