Contemporary insights into the functional anatomy of the mitral valve

Am Heart J. 2009 Dec;158(6):887-95. doi: 10.1016/j.ahj.2009.10.014.


The mitral valve is a highly complex structure the normal functioning of which requires the coordinated interaction of the leaflets, annulus, chordae tendineae, and papillary muscles. Perturbations of any of these components can interfere with normal valve function. The integrity of the mitral valve is also essential to maintaining normal left ventricular geometry and function through closely coupled ventricular-valvular interactions. This review summarizes recent developments in our understanding of the anatomy and physiology of the mitral valve.

Publication types

  • Review

MeSH terms

  • Chordae Tendineae / anatomy & histology
  • Chordae Tendineae / physiology
  • Humans
  • Mitral Valve / anatomy & histology*
  • Mitral Valve / physiology*