From floated to conventional confidence intervals for the relative risks based on published dose-response data

Comput Methods Programs Biomed. 2010 Apr;98(1):90-3. doi: 10.1016/j.cmpb.2009.11.005. Epub 2009 Dec 2.


A dose-response meta-analysis of epidemiological studies can encounter different types of confidence intervals (floated vs. conventional). This paper illustrates how to back calculate conventional confidence intervals from a set of relative risks reported with floated confidence intervals or floated standard errors. Furthermore, we provide an implementation of the formulas in a user-friendly program developed for Stata software. I exemplify the point using published data about alcohol intake and endometrial cancer incidence from the Million Women Study.

Publication types

  • Meta-Analysis

MeSH terms

  • Alcohol Drinking / epidemiology*
  • Confidence Intervals
  • Diagnosis, Computer-Assisted
  • Dose-Response Relationship, Drug
  • Endometrial Neoplasms / epidemiology*
  • Female
  • Humans
  • Risk Assessment
  • Risk*
  • Software
  • United States / epidemiology