Campylobacter jejuni as a cause of acute diarrhoea in children: a study at an urban hospital in Bangladesh

J Trop Med Hyg. 1991 Feb;94(1):50-4.


The importance of C. jejuni as an aetiological agent of childhood diarrhoea was investigated at an urban children's hospital in Dhaka over a period of 1 year. C. jejuni was isolated from 25.5% of 102 diarrhoeal patients compared to 8.6% of 93 age and sex-matched healthy control children studied (P less than 0.002). The organism was isolated as a single pathogen in 17.6% of diarrhoeal patients. No C. coli was detected. The infection rate was significantly higher (P less than 0.05) amongst children up to 1 year of age (32.8%) compared to those aged over 1 year (15.9%). The clinical features of the majority of Campylobacter-positive cases resembled toxin-mediated secretory type diarrhoea. A fourfold rise of antibody titre against autologous Campylobacter strains was observed in the convalescent sera of Campylobacter-positive cases. The findings strongly suggest that C. jejuni is an important aetiological agent of childhood diarrhoea amongst Bengali children and therefore should be looked for in diarrhoeal illness.

MeSH terms

  • Acute Disease
  • Bangladesh
  • Campylobacter Infections / complications*
  • Campylobacter jejuni*
  • Child
  • Child, Preschool
  • Diarrhea / microbiology*
  • Diarrhea, Infantile / microbiology
  • Hospitals, Urban
  • Humans
  • Infant