Staphylococcus aureus community-onset pneumonia in patients admitted to children's hospitals during autumn and winter of 2006-2007

Epidemiol Infect. 2010 May;138(5):666-72. doi: 10.1017/S095026880999135X. Epub 2009 Dec 7.

Abstract

Staphylococcus aureus is a relatively uncommon cause of community-onset pneumonia (COP) that may complicate influenza infection. We reviewed admissions to children's hospitals to describe more systematically this entity. Records of patients hospitalized at three children's hospitals between 1 October 2006 and 30 April 2007 who had a positive S. aureus culture from a sterile site or respiratory specimen were reviewed and data were abstracted for episodes of primary S. aureus COP. Overall, 30 episodes met criteria for primary S. aureus COP; 12 (41%) involved methicillin-resistant S. aureus. Patients in 11 (37%) episodes were seen by a healthcare provider for their symptoms prior to hospital admission; three received an antimicrobial, none of which had activity against the S. aureus isolated. Mechanical ventilation was required in 21 (70%) episodes; five (17%) patients died. When evaluating patients with severe COP, providers should be aware of the potential for S. aureus, including methicillin-resistant strains.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Community-Acquired Infections / epidemiology*
  • Community-Acquired Infections / microbiology
  • Female
  • Hospitalization
  • Humans
  • Infant
  • Male
  • Methicillin Resistance
  • Pneumonia, Staphylococcal / epidemiology*
  • Pneumonia, Staphylococcal / microbiology
  • Pneumonia, Staphylococcal / mortality
  • Respiration, Artificial
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / isolation & purification*

Substances

  • Anti-Bacterial Agents