Recombination in vaccine and circulating strains of porcine reproductive and respiratory syndrome viruses

Bin Li; Liurong Fang; Zuofei Xu; Suyan Liu; Jianfeng Gao; Yunbo Jiang; Huanchun Chen; Shaobo Xiao

doi:10.3201/eid1512.090390

Recombination in vaccine and circulating strains of porcine reproductive and respiratory syndrome viruses

Emerg Infect Dis. 2009 Dec;15(12):2032-5. doi: 10.3201/eid1512.090390.

Authors

Bin Li¹, Liurong Fang, Zuofei Xu, Suyan Liu, Jianfeng Gao, Yunbo Jiang, Huanchun Chen, Shaobo Xiao

Affiliation

¹ Huazhong Agricultural University, Wuhan 430070, People's Republic of China.

Abstract

Em2007, a porcine reproductive and respiratory syndrome virus (PRRSV) variant with a unique 68 aa deletion in Nsp2, was recently isolated in China. Phylogenetic and molecular evolutionary analyses indicated that Em2007 is a natural recombinant between a vaccine strain of PRRSV and circulating virus. We also tested its pathogenicity in piglets.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Open Reading Frames
Phylogeny
Porcine respiratory and reproductive syndrome virus / classification
Porcine respiratory and reproductive syndrome virus / genetics*
Recombination, Genetic*
Swine
Viral Vaccines

Substances

Viral Vaccines