Abstract
A question with respect to asthma therapy revolves around the issue of whether better efficacy occurs with an ultrafine-particle inhaled corticosteroid because of better lung deposition into the distal airways. This article reviews particle size and delivery devices of different steroids, clinical outcomes of small- versus large-particle steroids, and the issue of pharmacoeconomics.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Administration, Inhalation
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Adrenal Cortex Hormones* / administration & dosage
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Adrenal Cortex Hormones* / economics
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Adrenal Cortex Hormones* / therapeutic use
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Anti-Asthmatic Agents* / administration & dosage
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Anti-Asthmatic Agents* / economics
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Anti-Asthmatic Agents* / therapeutic use
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Asthma / drug therapy*
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Beclomethasone / administration & dosage
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Beclomethasone / economics
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Beclomethasone / therapeutic use
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Clinical Trials as Topic
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Dose-Response Relationship, Drug
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Humans
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Particle Size*
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Treatment Outcome
Substances
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Adrenal Cortex Hormones
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Anti-Asthmatic Agents
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Beclomethasone