Outcomes of conservative therapy for young women with early endometrial adenocarcinoma

Yuyan Mao; Xiaoyun Wan; Yaxia Chen; Weiguo Lv; Xing Xie

doi:10.1016/j.fertnstert.2009.07.999

Outcomes of conservative therapy for young women with early endometrial adenocarcinoma

Fertil Steril. 2010 Jan;93(1):283-5. doi: 10.1016/j.fertnstert.2009.07.999. Epub 2009 Dec 3.

Authors

Yuyan Mao¹, Xiaoyun Wan, Yaxia Chen, Weiguo Lv, Xing Xie

Affiliation

¹ Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.

PMID: 19962142
DOI: 10.1016/j.fertnstert.2009.07.999

Abstract

Four of six patients with endometrial cancer had initial response to progesterone therapy and obtained complete response; three among them had successful pregnancies with three live births. The results suggest that progesterone therapy, combined with assisted reproductive technology, provides more chance of carrying a full-term pregnancy for patients with endometrial adenocarcinoma.

MeSH terms

Adenocarcinoma / drug therapy*
Adenocarcinoma / pathology
Adenocarcinoma / physiopathology
Adult
Antineoplastic Agents, Hormonal / therapeutic use*
Endometrial Neoplasms / drug therapy*
Endometrial Neoplasms / pathology
Endometrial Neoplasms / physiopathology
Female
Fertility / drug effects*
Humans
Medroxyprogesterone Acetate / therapeutic use*
Megestrol Acetate / therapeutic use*
Neoplasm Staging
Pregnancy
Pregnancy Outcome
Reproductive Techniques, Assisted*
Retrospective Studies
Treatment Outcome

Substances

Antineoplastic Agents, Hormonal
Medroxyprogesterone Acetate
Megestrol Acetate