Green tea consumption improves endothelial function but not circulating endothelial progenitor cells in patients with chronic renal failure

Int J Cardiol. 2010 Nov 19;145(2):261-262. doi: 10.1016/j.ijcard.2009.09.471. Epub 2009 Dec 3.


This study was designed to determine the effect of green tea consumption in patients with chronic kidney disease (CKD) on flow-mediated endothelium-dependent vasodilation (FMD) and the number of circulating endothelial progenitor cells (EPCs). Forty patients with CKD requiring chronic dialysis were enrolled. The patients were divided into two groups: the catechin group that consumed green tea (5 g/day for 1 month) and the control group that consumed water. The number of EPCs, inflammatory markers, oxidative stress, and FMD were determined at baseline and 4 weeks after green tea consumption. Clinical characteristics, oxidative stress, inflammatory markers, and circulating EPCs number were not significantly different. FMD was significantly improved after 4 weeks in the catechin group (from 5.68±2.67% to 8.66±3.46%, p=0.002). Short-term green tea consumption induced a rapid improvement in FMD, but did not improve circulating EPC levels in patients with CKD.

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Endothelium, Vascular / pathology
  • Endothelium, Vascular / physiology*
  • Follow-Up Studies
  • Humans
  • Kidney Failure, Chronic / blood*
  • Kidney Failure, Chronic / diet therapy*
  • Kidney Failure, Chronic / pathology
  • Oxidative Stress / physiology
  • Stem Cells / pathology
  • Stem Cells / physiology*
  • Tea*


  • Tea