Blumeaxanthene II, a novel xanthene from Blumea riparia DC

Fitoterapia. 2010 Jul;81(5):389-92. doi: 10.1016/j.fitote.2009.11.009. Epub 2009 Dec 4.

Abstract

A novel xanthene (1), blumeaxanthene II, was isolated from the aerial parts of Blumea riparia (Bl.) DC., a Chinese medicinal plant with hemostatic properties, and its structure was determined by extensive spectroscopic analyses. This compound is the first example of a halogenated xanthene from a natural plant, and a biosynthetic pathway was proposed. Blumeaxanthene II was also tested against Bel-7404 cells in vitro but was found to be only weakly cytotoxic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asteraceae / chemistry*
  • Cell Line, Tumor
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / therapeutic use
  • Humans
  • Liver Neoplasms / drug therapy
  • Molecular Structure
  • Plant Components, Aerial
  • Xanthenes / chemistry
  • Xanthenes / isolation & purification*
  • Xanthenes / therapeutic use

Substances

  • Drugs, Chinese Herbal
  • Xanthenes
  • blumeaxanthene II