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. 2009 Nov 20;326(5956):1112-5.
doi: 10.1126/science.1178534.

The B73 Maize Genome: Complexity, Diversity, and Dynamics

Patrick S Schnable  1 Doreen WareRobert S FultonJoshua C SteinFusheng WeiShiran PasternakChengzhi LiangJianwei ZhangLucinda FultonTina A GravesPatrick MinxAmy Denise ReilyLaura CourtneyScott S KruchowskiChad TomlinsonCindy StrongKim DelehauntyCatrina FronickBill CourtneySusan M RockEddie BelterFeiyu DuKyung KimRachel M AbbottMarc CottonAndy LevyPamela MarchettoKerri OchoaStephanie M JacksonBarbara GillamWeizu ChenLe YanJamey HigginbothamMarco CardenasJason WaligorskiElizabeth ApplebaumLindsey PhelpsJason FalconeKrishna KanchiThynn ThaneAdam ScimoneNay ThaneJessica HenkeTom WangJessica RuppertNeha ShahKelsi RotterJennifer HodgesElizabeth IngenthronMatt CordesSara KohlbergJennifer SgroBrandon DelgadoKelly MeadAsif ChinwallaShawn LeonardKevin CrouseKristi ColluraDave KudrnaJennifer CurrieRuifeng HeAngelina AngelovaShanmugam RajasekarTeri MuellerRene LomeliGabriel ScaraAra KoKrista DelaneyMarina WissotskiGeorgina LopezDavid CamposMichele BraidottiElizabeth AshleyWolfgang GolserHyeRan KimSeunghee LeeJinke LinZeljko DujmicWoojin KimJayson TalagAndrea ZuccoloChuanzhu FanAswathy SebastianMelissa KramerLori SpiegelLidia NascimentoTheresa ZutavernBeth MillerClaude AmbroiseStephanie MullerWill SpoonerApurva NarechaniaLiya RenSharon WeiSunita KumariBen FagaMichael J LevyLinda McMahanPeter Van BurenMatthew W VaughnKai YingCheng-Ting YehScott J EmrichYi JiaAnanth KalyanaramanAn-Ping HsiaW Brad BarbazukRegina S BaucomThomas P BrutnellNicholas C CarpitaCristian ChaparroJer-Ming ChiaJean-Marc DeragonJames C EstillYan FuJeffrey A JeddelohYujun HanHyeran LeePinghua LiDamon R LischSanzhen LiuZhijie LiuDawn Holligan NagelMaureen C McCannPhillip SanMiguelAlan M MyersDan NettletonJohn NguyenBryan W PenningLalit PonnalaKevin L SchneiderDavid C SchwartzAnupma SharmaCarol SoderlundNathan M SpringerQi SunHao WangMichael WatermanRichard WestermanThomas K WolfgruberLixing YangYeisoo YuLifang ZhangShiguo ZhouQihui ZhuJeffrey L BennetzenR Kelly DaweJiming JiangNing JiangGernot G PrestingSusan R WesslerSrinivas AluruRobert A MartienssenSandra W CliftonW Richard McCombieRod A WingRichard K Wilson
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Free article

The B73 Maize Genome: Complexity, Diversity, and Dynamics

Patrick S Schnable et al. Science. .
Free article

Erratum in

  • Science. 2012 Aug 31;337(6098):1040

Abstract

We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an important crop plant and model for biological research. Over 32,000 genes were predicted, of which 99.8% were placed on reference chromosomes. Nearly 85% of the genome is composed of hundreds of families of transposable elements, dispersed nonuniformly across the genome. These were responsible for the capture and amplification of numerous gene fragments and affect the composition, sizes, and positions of centromeres. We also report on the correlation of methylation-poor regions with Mu transposon insertions and recombination, and copy number variants with insertions and/or deletions, as well as how uneven gene losses between duplicated regions were involved in returning an ancient allotetraploid to a genetically diploid state. These analyses inform and set the stage for further investigations to improve our understanding of the domestication and agricultural improvements of maize.

Comment in

  • Plant science. Solving the maze.
    Feuillet C, Eversole K. Feuillet C, et al. Science. 2009 Nov 20;326(5956):1071-2. doi: 10.1126/science.1183463. Science. 2009. PMID: 19965417 No abstract available.

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