Why and how bacteria localize proteins

Science. 2009 Nov 27;326(5957):1225-8. doi: 10.1126/science.1175685.


Despite their small size, bacteria have a remarkably intricate internal organization. Bacteria deploy proteins and protein complexes to particular locations and do so in a dynamic manner in lockstep with the organized deployment of their chromosome. The dynamic subcellular localization of protein complexes is an integral feature of regulatory processes of bacterial cells.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Bacteria / cytology
  • Bacteria / metabolism*
  • Bacteria / ultrastructure
  • Bacterial Proteins / metabolism*
  • Cell Division
  • Cell Membrane / physiology
  • Cell Membrane / ultrastructure
  • Chemotaxis
  • Chromosomes, Bacterial / physiology
  • Diffusion
  • Intracellular Space / metabolism
  • Protein Binding


  • Bacterial Proteins