Pimelotides A and B, diterpenoid ketal-lactone orthoesters with an unprecedented skeleton from Pimelea elongata

Patricia Y Hayes; Sharon Chow; Michael J Somerville; James J De Voss; Mary T Fletcher

doi:10.1021/np900573k

Pimelotides A and B, diterpenoid ketal-lactone orthoesters with an unprecedented skeleton from Pimelea elongata

J Nat Prod. 2009 Dec;72(12):2081-3. doi: 10.1021/np900573k.

Authors

Patricia Y Hayes¹, Sharon Chow, Michael J Somerville, James J De Voss, Mary T Fletcher

Affiliation

¹ School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, 4072, Australia, and Queensland Primary Industries and Fisheries, Locked Mail Bag 4 Moorooka, 4105, Australia.

PMID: 19968293
DOI: 10.1021/np900573k

Abstract

A detailed investigation of the minor phytochemical components of Pimelea elongata foliage led to the discovery of two new diterpenoid daphnane ketal-lactone orthoesters with an unprecedented skeleton, pimelotides A (1) and B (2). Their structures and relative configurations were elucidated by NMR spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Australia
Diterpenes / chemistry
Diterpenes / isolation & purification*
Lactones / chemistry
Lactones / isolation & purification*
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Thymelaeaceae / chemistry*

Substances

Diterpenes
Lactones
pimelotide A
pimelotide B