Treatment of class III multiple gingival recessions: a randomized-clinical trial

J Clin Periodontol. 2010 Jan;37(1):88-97. doi: 10.1111/j.1600-051X.2009.01492.x. Epub 2009 Nov 30.


Background: The aim of this controlled randomized split-mouth study was to evaluate whether a modified tunnel/connective tissue graft (CTG) technique - enamel matrix derivative (EMD) combination will improve the treatment of multiple class III recession when compared with the same technique alone.

Materials and methods: Twenty healthy subjects with a mean age of 31.7 years, were enrolled for the trial in a university periodontal clinic. Patients with at least three adjacent gingival recessions on both sides of the mouth were treated with a modified tunnel/CTG technique. On the test side, an EMD was used in addition. Clinical parameters were measured at baseline, 28 days, 3, 6 and 12 months after the surgery. Results are presented at the subject level.

Results: The mean root coverage from baseline to 1 year post-surgery was 82% for the test group and 83% for the control group. Complete root coverage was achieved at 1 year in eight (38%) of the 20 surgeries (experimental and control group).

Conclusions: One-year results indicate that the modified tunnel/CTG technique is predictable for the treatment of multiple class III recession-type defects. The addition of EMD does not enhance the mean clinical outcomes.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Connective Tissue / transplantation
  • Dental Enamel Proteins / therapeutic use
  • Dental Plaque Index
  • Follow-Up Studies
  • Gingiva / transplantation
  • Gingival Recession / classification
  • Gingival Recession / surgery*
  • Gingivoplasty / methods
  • Humans
  • Periodontal Attachment Loss / classification
  • Periodontal Index
  • Periodontal Pocket / classification
  • Surgical Flaps / pathology
  • Suture Techniques
  • Tooth Root / pathology
  • Tooth Root / surgery
  • Treatment Outcome
  • Wound Healing / physiology


  • Dental Enamel Proteins
  • enamel matrix proteins